Banner Head 
 

WEBINARS 
 
         
         
         
INNOVATION IN THE ED: THE ROLE OF BIOMARKERS FOR THE EVALUATION OF MILD TRAUMATIC BRAIN INJURY

Live event: November 10, 2022

An estimated 69 million patients
1 worldwide sustain a traumatic brain injury (TBI) each year of which more than 80% are classified as mild (GCS 13 to 15)2. Due to the limitations of current evaluation tools, mTBI assessment can be time- and resource-consuming.

In the ED, the evaluation, diagnosis, and clinical decision making for patients suspected of mild traumatic brain injury (mTBI) can be challenging especially when an accurate history is not easily obtained, or patients are difficult to scan. In addition, current evaluation tools and techniques used in the ED are often subjective, resource consuming, or have low diagnostic yield. Join us as 2 experts provide the latest research and innovative approaches to improve patient care.

New developments in the use of brain injury biomarkers to help the assessment of patients suspected of mTBI have promise to aid in the evaluation and provide objectivity in conjunction with other clinical information. Two proteins in particular, Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and Glial fibrillary acidic protein (GFAP), have the potential to reduce unnecessary CT scans, and improve operational efficiency.


1
Dewan MC et al. J Neurosurg. 2004;43(suppl):113-125.
2
Korley FK et al. J Head Trauma Rehabil. 2016;31(6):379-387.  
  Jeffrey Bazarian photo

JEFFREY BAZARIAN, MD, MPH

Dr. Bazarian is tenured Professor of Emergency Medicine and Neurology at the University of Rochester He is a graduate of Brown University and the University of Rochester School of Medicine and Dentistry. His research uses advanced brain imaging, helmet sensors and blood sampling to investigate the effects of concussion and repetitive head hits on the brain. Dr. Bazarian was the lead author on the 2018 Lancet Neurology publication detailing the results of the multi-national study that was used to support FDA approval for the first blood-based biomarkers of traumatic brain injury in the US. He currently sees concussion patients in URMCs Child Neurology Clinic.
  Chris Devlantes photo

CHRIS DAVLANTES, MD, FACEP

Dr. Davlantes is the Sr. Director of Global Medical Affairs at Abbott Point of Care. Board-certified by the American Board of Emergency Medicine, he has practiced Emergency Medicine for over 25 years and is a Fellow of the American College of Emergency Physicians. Dr. Davlantes has been an Assistant Professor at the University of Kansas Hospital for the past 9 years, and is still practicing Emergency Medicine part-time at Northwell Health system’s Lenox Health Greenwich Village, a free-standing ED. Dr. Davlantes has worked as a global Medical Affairs leader in the medical device industry since 2012, where his focus and passion is to bridge innovative technologies with clinical unmet needs to improve patient outcomes around the globe.

       
Learning Objectives: 

Examine challenges and shortcomings with current approaches to mTBI evaluation in the ED and review how to address them through the latest research and innovations
Review the latest advancements in TBI biomarkers, including identifying brain-specific biomarkers with characteristics that offer diagnostic value in the ED
Describe how blood plasma-based biomarker testing can be used in conjunction with other clinical information to aid in the evaluation of suspected mTBI patients and reduce diagnostic uncertainty
Demonstrate how biomarker-based testing can provide objective assessment of suspected mTBI and examine the potential to reduce unnecessary head CT, improve patient care and satisfaction, and improve operational efficiency 
         
Recording   Slides
 
       
         
Learn More
 
       

       
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563    
         

         
         
         
USING NEW TOOLS AND TECHNIQUES TO ADVANCE CARE FOR MILD TRAUMATIC BRAIN INJURY IN THE ED

Live event: June 8, 2022

In the ED, the evaluation, diagnosis and clinical decision for patients suspected of mild traumatic brain injury (mTBI) is often challenging. Current evaluation tools and techniques used in the ED are often subjective, resource consuming, or have low diagnostic yield. Join us as 2 experts provide the latest research and innovative approaches to improve patient care.

New developments in the use of brain injury biomarkers to help the assessment of patients suspected of mTBI have promise to aid in the evaluation and provide objectivity in conjunction with other clinical information. Furthermore, significant progress has been made to understand how physiologic, social, and environmental factors impact the clinical manifestations of mTBI patients. Understanding the mechanism and location of injury may facilitate improved patient management and inform treatment.

Learning Objectives:

Review the latest research, best practices, challenges and developments to advance assessment and care for patients suspected of mTBI
Demonstrate how biomarker-based testing can provide objective assessment of suspected mTBI and examine the potential to reduce unnecessary head CT, improve patient care and satisfaction, and improve operational efficiency
Examine how physiologic, social, and environmental factors impact the clinical manifestations if mTBI/concussion
Illustrate a multidisciplinary approach to the neurobehavioral presentations of mTBI patients post ED-discharge

  Silvana Riggio photo

SILVANA RIGGIO, MD

Silvana Riggio, MD, Professor of Neurology and Psychiatry, Rehabilitation Medicine and Human Performance, Icahn School of Medicine at Mount Sinai
Dr. Riggio is a Professor of Neurology, Psychiatry and Rehabilitation Medicine at the Icahn School of Medicine at Mount Sinai. Dr. Riggio trained in Neurology at Georgetown University and fellowship trained in neuro-electrophysiology at John Hopkins and in Clinical Epilepsy at the Medical College of Pennsylvania. She served as the Co-Director of the Mid- Epilepsy Center and the Director of the Epilepsy Program at Mayo Clinic Jacksonville.

Dr. Riggio also trained in Psychiatry at Cornell Weill Medical Center. Dr. Riggio has lectured globally and participated on National Committees related to TBI including the ACEP-CDC guidelines task force on mild TBI published in December 2008 and a CDC project on discharge instructions for mild TBI patients. She was a task force member of the CDC/DoD Concussion definition consortium, the Medical Director for the NFL Neurological Care Program at Mount Sinai and served as an independent Neuro Trauma Consultant for the NFL. Dr. Riggio has authored over 50 articles and book chapters, has edited 7 books and journal supplements, and co-authored one book. She has also been the primary investigator or co-investigator for 22 grants.

  Chris Devlantes photo 

CHRIS DAVLANTES, MD, FACEP

Chris Davlantes, MD, FACEP, Emergency Medicine Physician, Senior Director, Global Medical Affairs, Abbott
Dr. Davlantes is the Sr. Director of Global Medical Affairs at Abbott Point of Care. Board-certified by the American Board of Emergency Medicine, he has practiced Emergency Medicine for over 25 years and is a Fellow of the American College of Emergency Physicians. He completed his medical school training at Indiana University School of Medicine and his residency training at University of Illinois’ College of Medicine in Peoria.

Dr. Davlantes has held the position of Assistant Professor in the Department of Emergency Medicine at the University of Kansas Hospital for the past 9 years, and he is still practicing Emergency Medicine part-time at Northwell Health system’s Lenox Health Greenwich Village, a free-standing ED located in Manhattan, New York City, where he and his wife relocated during the beginning of the COVID-19 pandemic. Dr. Davlantes has been working as a global Medical Affairs leader in the medical device industry since 2012, where his focus and passion has been to bridge innovative technologies with clinical unmet needs in order to improve patient outcomes around the globe.
         
Recording   Slides
 
Learn More
         
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563   
         

 
         
         
CHALLENGES IN MILD TRAUMATIC BRAIN INJURY (MTBI) ASSESSMENT AND THE NEXT FRONTIER IN BIOMARKER TESTING

Live event: November 11, 2021

An estimated 69 million patients1 worldwide sustain a traumatic brain injury (TBI) each year of which more than 80% are classified as mild (GCS 13 to 15)2. Due to the limitations of current evaluation tools, mTBI assessment can be time- and resource-consuming.


Join leading experts in an upcoming webinar to learn about the latest research into blood plasma-based biomarkers and their potential to predict the absence of intracranial injury. During this webinar, you’ll hear how two proteins, Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and Glial fibrillary acidic protein (GFAP), have emerged as promising biomarkers that can be used in conjunction with other clinical information to aid in the evaluation of suspected mTBI patients in the ED.

1Dewan MC et al. J Neurosurg. 2004;43(suppl):113-125.
2Korley FK et al. J Head Trauma Rehabil. 2016;31(6):379-387.


Learning Objectives:

Examine challenges and shortcomings of the current approaches to mTBI evaluation in the ED
Review the latest advancements in TBI biomarkers, including identifying brain-specific biomarkers with characteristics that offer diagnostic value in the ED
Describe how blood plasma-based biomarker testing can be used in conjunction with other clinical information to aid in the evaluation of suspected mTBI patients and reduce diagnostic uncertainty by providing the quantitative measurement of biomarkers producing an objective interpretation.
Examine the potential for biomarker testing to reduce unnecessary head CT, improve patient care and satisfaction, and improve operational efficiency

  Peter Biberthanler photo

PROFESSOR PETER BIBERTHALER, MD

Professor Peter Biberthaler’s research activities concentrate on his core clinical focus areas. A very important aspect of these focus areas is the care of severe and multiple trauma patients, a major part of which is the treatment of traumatic brain injuries.

Professor Biberthaler’s other major focus area, shoulder surgery, is the logical consequence of his scientific research and clinical practice in the field of traumatology. He is the first person to have been able to visualize the blood circulation in direct proximity to ruptures by means of intraoperative intravital-microscopic imaging.
  Paul Jarvis photo 

PAUL JARVIS, MD, BSC(HONS) MBCHB MRCP FRCEM DIP MED ED MSC

Dr. Jarvis is the Director of Global Medical Affairs at Abbott Point of Care. In addition, he is a practicing Emergency Medicine Physician working in the North of England. He has over 20 years of clinical experience with particular interests in Neurological Emergencies and Trauma management. He has a Masters Degree in Quality Improvement from Ashridge Business School, United Kingdom. Parallel to his clinical work, Paul ran a global management consultancy for 5 years, helping hospitals around the world improve their patient flow.
         
Recording   Slides
 
Learn More
         
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563   
         

         

USING BIOMARKERS FOR OBJECTIVE ASSESSMENT OF MILD TRAUMATIC BRAIN INJURY

Live event: July 22, 2021

Traumatic brain injury (TBI) is evaluated during ~5 million ED visits annually1 of which more than 80% are classified as mild (GCS 13 to 15)2. Due to the limitations of current evaluation tools, mTBI assessment can be time- and resource-consuming.

Join leading experts in an upcoming webinar to learn about the latest research into blood-based biomarkers and their potential to predict the absence of intracranial injury. During this webinar, you’ll hear how two proteins, Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and Glial fibrillary acidic protein (GFAP), have emerged as promising biomarkers that can be used in conjunction with other clinical information to aid in the evaluation of suspected mTBI patients in the ED.


1Korley FK et al. J Head Trauma Rehabil. 2016;31(6):379-387.
2Dewan MC et al. J Neurosurg. 2004;43(suppl):113-125.


Learning Objectives:
Examine challenges and shortcomings of the current approaches to mTBI evaluation in the ED

Review the latest advancements in TBI biomarkers, including identifying brain-specific biomarkers with characteristics that offer diagnostic value in the ED

Describe how blood-based biomarker testing can be used in conjunction with other clinical information to aid in the evaluation of suspected mTBI patients and reduce diagnostic uncertainty by providing a quantifiable objective assessment

Examine the potential for biomarker testing to reduce unnecessary head CT, improve patient care and satisfaction, and improve operational efficiency

 

Vertical Line gray Jesse Pines photo 

JESSE M. PINES, MD, MBA, MSCE

Jesse Pines MD, is the National Director of Clinical Innovation at US Acute Care Solutions and a Professor of Emergency Medicine at Drexel University. Dr. Pines leads USACS’s efforts in telemedicine, alternative payment models, and opioids. Dr. Pines is a nationally known expert in ED quality of care, innovation, and health services research, and has published more than 330 peer-reviewed publications and six books. Before joining USACS in 2018, he served as the Director of the Center for Healthcare Innovation and Policy Research and Professor at George Washington University and Professor, and also previously was Assistant Professor at the University of Pennsylvania.




Paul Jarvis Photo

PAUL JARVIS, MD, BSC(HONS) MBCHB MRCP FRCEM DIP MED ED MSC

Dr. Paul Jarvis is the Director of Global Medical Affairs at Abbott Point of Care. In addition, he is a practicing Emergency Medicine Physician working in the North of England. He has over 20 years of clinical experience with particular interests in Neurological Emergencies and Trauma management. He has a Masters Degree in Quality Improvement from Ashridge Business School, United Kingdom. Parallel to his clinical work, Paul ran a global management consultancy for 5 years, helping hospitals around the world improve their patient flow.
Vertical Gray line Jeffrey Bazarian photo

JEFFREY BAZARIAN, MD


Dr. Jeffrey Bazarian is a Professor of Emergency Medicine and Neurology with an active, interdisciplinary, clinical research program in mild TBI and sport concussions at the University of Rochester. He has served as the lead investigator on projects to determine the epidemiology and outcome of mild TBI (K23 from NINDS), to image with DTI axonal injury acutely after mild TBI (R01 from NICHD), to determine the role of serum S100B in the diagnosis of intracranial hemorrhage after mild TBI (New York State Department of Health), to validate new putative markers of axonal injury (K24 NICHD), and to investigate the nature of white matter damage after multiple sub-concussive head blows (NFL-Charities). His lab’s translational research platform involving contact athletes at the University of Rochester and Rochester Institute of Technology incorporates DTI, fMRI, and cognitive/balance performance with head accelerometer data, as well as with serum and whole blood sampling for protein and genetic analysis, respectively.
Recording   Slides
 
Learn More
 
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563  
 

 

TRAUMATIC BRAIN INJURY BEST PRACTICES AND OPPORTUNITIES: FROM ACUTE EVALUATION TO POST-DISCHARGE

Live event: December 7, 2020

Worldwide each year, 50 million+ people sustain a traumatic brain injury (TBI). Symptoms resolve quickly for many patients, while others can take several weeks to months for post-concussive symptoms to resolve, and yet another subset of patients continue to experience persistent symptoms for 3 months or more after injury. However, due to the limitations of currently used evaluation tools, TBI can be challenging to adequately screen, manage and develop therapeutic treatments to improve outcomes.

Hear from leading experts about effective strategies and trends related to head injury evaluation and an update regarding potential advances in biomarker research. Biomarkers have the potential to aid in the evaluation of TBI and have demonstrated the ability to predict the absence of intracranial injury. Two proteins, Ubiquitin C-terminal hydrolase-L1 (UCH-L1) and Glial fibrillary acidic protein (GFAP), have emerged as promising biomarkers for clinical use to predict traumatic intracranial injuries on head CT scan acutely after TBI.


Learning Objectives:
Describe unmet needs and challenges regarding the current tools and approach to traumatic brain injury evaluation
Examine how the current approach to TBI evaluation impacts patient care and burden to the hospital
Discuss the long-term impact of mild TBI and what Emergency Departments can do to improve outcomes
Identify developments regarding the use of biomarkers for TBI evaluation and discuss the ways in which biomarkers may be used in the future clinically to improve patient care

 

Vertical Line gray Alastair Jones photo 
ALASTAIR M. JONES, MBCHB, FRCEM, PGDIP

Dr Alastair Jones is a Consultant in Emergency Medicine at the Bradford Teaching Hospitals Foundation Trust. Alastair qualified in Medicine from the University of Sheffield in 2003. He obtained Fellowship to the Royal College of Emergency Medicine in 2011 and Membership to the Faculty of Sports and Exercise Medicine in 2019. He also achieved a Post-Graduate Diploma in Sports and Exercise Medicine from the University of Bath in 2016. His areas of clinical interest include Musculoskeletal Medicine, Sports and Exercise Medicine, and Sports Concussion. Alastair developed and leads the Bradford Royal Infirmary Acute Musculoskeletal Clinic, a multidisciplinary clinic for patients with musculoskeletal injuries.

Dr. Jones is also heavily involved in Sports and Exercise Medicine and held the post of Head of Medical Services for Leeds Rugby where he oversaw the medical departments of both Leeds Rhinos Rugby League and Yorkshire Carnegie Rugby Union. He currently provides medical services for the Rugby Football Union as the course director for the Rugby Football Unions Pre-Hospital Immediate Care in Sport Course and forms part of the Twickenham Stadium international match day medical team. He also works as a match day doctor for Premiership Rugby. Dr. Jones previously worked for Tonga during the 2013 Rugby League World Cup and held the role of Immediate Care Doctor at the 2015 Rugby Union World Cup and 2016 Rugby Union Junior World Cup.
Vertical Gray line Thomas Watanabe photo
THOMAS K. WATANABE, MD

Thomas Watanabe, MD is Clinical Director of the Drucker Brain Injury Center at MossRehab, director of the MossRehab Stroke program and Associate Professor in the Department of Physical Medicine and Rehabilitation at the Temple University School of Medicine in Philadelphia. He oversees the clinical aspects of the inpatient and outpatient brain injury and stroke programs as well as participating in the strategic planning for programs at MossRehab in general. He is also actively involved in the training of residents and medical students in the medical care and rehabilitation of persons with neurological diagnoses.

Dr. Watanabe is a co-investigator on the current Traumatic Brain Injury Model System grant supported by the NIDILRR and has participated in several other clinical trials related to recovery after stroke and brain injury. He has authored or co-authored several peer-reviewed articles directly related to the treatment of individuals with acquired brain injuries as well as other invited articles and book chapters. Dr. Watanabe is on the editorial board of The Journal of Head Trauma Rehabilitation. He has also given many local, regional, national and international presentations to health care professionals on various aspects of neurorehabilitative care.
 
Recording   Slides
 
Back to
TBI Resources
 
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563  
 
 
 

ADVANCES IN TRAUMATIC BRAIN INJURY EVALUATION AND MANAGEMENT

Live event: July 23, 2020

Worldwide each year, 50 million+ people sustain a traumatic brain injury (TBI); most cases are mild with variable clinical outcomes and lasting symptoms1. Hear from leading experts about effective strategies and trends related to head injury evaluation. The latest blood-based biomarker research and their potential to predict the absence of intracranial injury will also be presented.


This webinar will discuss how biomarkers may be used in the future clinically to improve patient care in the hospital and outpatient care setting. It will also identify the role of brain biomarker tests in the hospital performance.

Learning Objectives:
Describe unmet needs and challenges regarding the current tools and approach to traumatic brain injury evaluation
Examine how the current approach to TBI evaluation impacts patient care and burden to the hospital
Identify developments regarding the use of biomarkers for TBI evaluation
Discuss the ways in which biomarkers may be used in the future clinically to improve patient care in the hospital and outpatient care setting
Assess the role of brain biomarker tests in the hospital performance  

1 Nelson LD et al. Recovery after mild traumatic brain injury in patients presenting to US level I trauma centers. JAMA Neurol.2019;76(9):1049.

Vertical Line gray Jeffrey Bazarian Photo 
JEFFREY J. BAZARIAN, MD, MPH

Dr. Bazarian is Professor of Emergency Medicine and Neurology at the University of Rochester. He is a graduate of Brown University and the University of Rochester School of Medicine and Dentistry. He is board certified in Internal Medicine and Emergency Medicine but practiced Emergency Medicine exclusively for 22 years until 2012. In 2010, Dr. Bazarian joined the University of Rochester Sports Concussion Clinic, providing outpatient concussion care to area high school and collegiate athletes.

Dr Bazarian’s research is focused on developing neuroimaging and blood-based biomarkers of axonal injury after concussion and repetitive head hits, and the pathophysiologic mechanisms of recovery. He, along with Dr Welch, were lead authors on the 2018 Lancet Neurology publication detailing the results of the multi-national ALERT-TBI trial used to support FDA clearance of the first test to use blood-based biomarkers of traumatic brain injury in the US.

Vertical Gray line Robert Welch photo 
ROBERT D. WELCH, MD, MS, FACEP,

Dr. Welch is Professor, Clinical Educator, in the Department of Emergency Medicine and is the Director of the Biostatistics and Epidemiology Research Design Group. He is a member of the Cardiovascular Research Institute and an Associate in the Department of Physical Medicine and Rehabilitation at Wayne State University School of Medicine in Detroit, Michigan.

Dr. Welch completed his MD degree at Wayne State University School of Medicine, his residency in Emergency Medicine at Detroit Receiving Hospital / Wayne State University, and a M.S. in Clinical Research Design and Statistical Analysis at the University of Michigan. Rob’s interests include neurological emergencies, clinical trials methodology and heart disease. He was the Program Director of the Wayne State University Neurological Emergencies Treatment Trials Network from 2007 – 2018 and held numerous clinical research contracts with foundations and industry.

 
Recording   Slides
 
Back to
TBI Resources
 
One P.A.C.E.® contact hour will be provided for this basic level session for six months following the live event. Abbott is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This session is approved for one Florida CE credit. Florida Board of Clinical Laboratory Personnel approved number: 50-12563